Hypomagnesaemia may cause neurological symptoms as part of its presentation. This case demonstrates one such unusual example of a reversible cerebellar syndrome resulting from magnesium deficiency. An 81-year-old woman presented to the emergency department with a history of chronic tremor and other cerebellar signs. Severe hypomagnesaemia was detected within her initial biochemistry results. Correction of this deficiency led to a resolution in her symptoms.

References

1. Ryan MF. The role of magnesium in clinical biochemistry: an overview. Ann Clin Biochem. 1991 28 pp 19-26 https://journals.sagepub.com/doi/10.1177/000456329102800103?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
2. Bichara MD, Goldman RD. Magnesium for treatment of asthma in children. Can Fam Physician. 2009 55(9) pp 887–889. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743582/
3. Duley L, Gülmezoglu AM, Henderson-Smart DJ, Chou D. Magnesium sulphate and other anticonvulsants for women with pre-eclampsia. The Cochrane Database of Systematic Reviews. 2010 11 https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000025.pub2/full
4. Dietch D, Wilson A, Thomas A. Magnesium is underused in acute atrial fibrillation. BMJ 1996 312 pp 1101 https://www.bmj.com/content/312/7038/1101.3
5. Peebles D M, Marlow N, Brocklehurst P. Antenatal magnesium sulphate. BMJ 2010 341 https://www.bmj.com/content/341/bmj.c6004.short
6. Kamm CP, Nyffeler T, Henzen C, Fischli S. Hypomagnesemia-Induced Cerebellar Syndrome—A Distinct Disease Entity? Case Report and Literature Review. Front. Neurol. 2020 8. https://www.frontiersin.org/articles/10.3389/fneur.2020.00968/full
7. Shabajee N, Lamb E J, Sturgess I, Sumathipala R W. Omeprazole and refractory hypomagnesaemia. BMJ 2008 337 pp 425 https://www.bmj.com/content/337/bmj.39505.738981.BE.long
8. Havard C W H. Hypomagnesaemia and muscle function. Br Med J (Clin Res Ed) 1988 296 (6625) pp 861 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2545133/pdf/bmj00277-0061e.pdf
9. Gardin A, Giammello F, Toscano A, Musolino RF. Severe hypomagnesaemia as new potential stroke mimic: a case report. Neurological Sciences 2022 43 pp 4007-9 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923089/
10. Santos AF, Sousa F, Rodrigues M, Ferreira C, Soares-Fernandes JF, Maré R. Reversible cerebellar syndrome induced by hypomagnesemia. Neurology and Clinical Neuroscience 2015 3(5) pp 190-1 https://onlinelibrary.wiley.com/doi/full/10.1111/ncn3.183