Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care

Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care

Background: Deep vein thrombosis (DVT) is commonly managed in ambulatory care. Guidelines recommend reassessment at three months to review anticoagulation duration, but no structured follow-up pathway exists within our Trust.
Aim: To evaluate anticoagulation duration, follow-up practices, and outcomes in patients with DVT diagnosed in ambulatory care.
Methods: Retrospective, observational service evaluation across two ambulatory care units in Manchester, UK. Patients with confirmed lower limb DVT were identified between January 2023 and June 2023. Data were collected from electronic patient records including complication rates over a 2-year period.
Results: Of 307 patients assessed for suspected DVT, 90 had confirmed DVT. Most cases were unprovoked (77.8%). At discharge, 39% were prescribed 3 months’ anticoagulation, 31% 6 months, 11% lifelong, 6% received a duration range of 3-6 months, and 13% had no specified duration. Discrepancies between recommendation at discharge and primary care prescribing were seen in 53%, with nearly half receiving longer treatment. 20% had secondary care follow-up. Recurrent DVT occurred in nine patients, none of whom had received follow-up; no recurrences were seen in the followed-up group, although this difference was not statistically significant (Fisher’s exact test, p = 0.195). Bleeding events were seen in 4.4% of cases and were minor.
Conclusions: There is substantial variability in anticoagulation management following DVT in ambulatory care. Although recurrence was not observed in the followed-up group, the study was not powered to detect differences, and this finding should be interpreted cautiously. Further work is needed to establish if a follow-up DVT clinic will improve patient outcomes.

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Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care

11th June 2026
PMID: 42462216
Authors Affiliations
Adam Darnley Department of Medicine, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK
Thomas Knight Institute of Applied Health Research, University of Birmingham
Jecko Thachil Department of Haematology, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK

Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care

Cite this article as:

Darnley A, Knight T, Thachil J. Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care. Acute Med. 2025;24(4):164-167. doi: 10.52964/AMJA.1023. PMID: 42462216.

Variability in Anticoagulation Duration and Follow-up for Deep Vein Thrombosis in Ambulatory Care

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