The increased mortality associated with a weekend emergency admission is due to increased illness severity and altered case-mix

The increased mortality associated with a weekend emergency admission is due to increased illness severity and altered case-mix

Abstract

Background: A weekend emergency medical admission has been associated with a higher mortality. We have examined all weekend admissions to St James’ Hospital, Dublin between 2002 and 2009.

Methods: We divided admissions by weekday or weekend (Saturday or Sunday) presentation. We utilised a multivariate logistic model, to determine whether a weekend admission was independently predictive of 30 day outcome.

Results: There were 49337 episodes recorded in 25883 patients; 30-day inhospital mortality at the weekend (9.9% vs. 9.0%) had an unadjusted Odds Ratio of 1.11 (95% CI 0.99, 1.23: p=0.057). In the full risk (unlike the univariate) model, a weekend admission was not independently predictive (OR 1.05; 95% CI: 0.88, 1.24). The case-mix for a weekend admission differed; with more neurological diagnoses (22.8% vs 20.4% : p = 0.001) and less gastrointestinal disease (18.3% vs 21.1% : p = 0.001). A biochemistry only illness severity score predicted a higher mortality for weekend admissions.

Conclusion: Patients admitted at the weekend had an approximate 11% increased 30-day in-hospital mortality, compared with a weekday admission. However, admission at the weekend was not independently predictive in a risk model that included Illness Severity (age and biochemical markers) and co-morbidity. Sicker patients, with a worse outcome, are admitted over the weekend; these considerations should inform the allocation of healthcare resources.

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References

  1. Bell CM, Redelmeier DA. Mortality among patients admitted to hospitals on weekends as compared with weekdays. N Engl J Med. 2001; 345(9): 663-8.
  2. Aiken LH, Clarke SP, Sloane DM, et al. Hospital nurse staffing and patient mortality, nurse burnout, and job dissatisfaction. Jama. 2002; 288(16): 1987-93.
  3. Needleman J, Buerhaus P, Mattke S, et al. Nurse-staffing levels and the quality of care in hospitals. N Engl J Med. 2002; 346(22): 1715-22.
  4. Asch DA, Parker RM. The Libby Zion case. One step forward or two steps backward? N Engl J Med. 1988 Mar 24; 318(12): 771-5.
  5. Becker DJ. Do Hospitals Provide Lower Quality Care on Weekends? Health Services Research. 2007; 42(4): 1589-612.
  6. The impact of weekends on outcome for emergency patients. Clinical Medicine, Journal of the Royal College of Physicians. 2005; 5: 621-5.
  7. Maggs F, Mallet M. Mortality in out-of-hours emergency medical admissions--more than just a weekend effect. J R Coll Physicians Edinb. 2010; 40(2): 115-8.
  8. Chaim MB, Donald AR. Waiting for urgent procedures on the weekend among emergently hospitalized patients. The American Journal of Medicine. 2004; 117(3): 175-81.
  9. Bell CM, Redelmeier DA. Mortality among Patients Admitted to Hospitals on Weekends as Compared with Weekdays. New England Journal of Medicine. 2001; 345(9): 663-8.
  10. Barnett M. Day of the Week of Intensive Care Admission and Patient Outcomes: A Multisite Regional Evaluation. Medical care. 2002; 40(6): 530.
  11. Aylin P, Yunus A, Bottle A, et al. Weekend mortality for emergency admissions. A large, multicentre study. Qual Saf Health Care. 2010; 19(3): 213-7.
  12. Clarke MS, Wills RA, Bowman RV, et al. Exploratory study of the 'weekend effect' for acute medical admissions to public hospitals in Queensland, Australia. Intern Med J. 2010; 40(11): 777-83.
  13. Barnett MJ, Kaboli PJ, Sirio CA, Rosenthal GE. Day of the week of intensive care admission and patient outcomes: a multisite regional evaluation. Med Care. 2002; 40(6): 530-9.
  14. Chalfin DB, Trzeciak S, Likourezos A, et al. Impact of delayed transfer of critically ill patients from the emergency department to the intensive care unit. Crit Care Med. 2007 Jun; 35(6): 1477-83.
  15. Ensminger SA, Morales IJ, Peters SG, et al. The hospital mortality of patients admitted to the ICU on weekends. Chest. 2004; 126(4): 1292-8.
  16. Kostis WJ, Demissie K, Marcella SW, et al. Weekend versus weekday admission and mortality from myocardial infarction. N Engl J Med. 2007; 356(11): 1099-109.
  17. Peberdy MA, Ornato JP, Larkin GL, et al. Survival from in-hospital cardiac arrest during nights and weekends. Jama. 2008; 299(7): 785-92.
  18. Saposnik G, Baibergenova A, Bayer N, et al. Weekends: a dangerous time for having a stroke? Stroke. 2007; 38(4): 1211-5.
  19. Shaheen AA, Kaplan GG, Myers RP. Weekend versus weekday admission and mortality from gastrointestinal hemorrhage caused by peptic ulcer disease. Clin Gastroenterol Hepatol. 2009; 7(3): 303-10.
  20. Hoh BL, Chi YY, Waters MF, et al. Effect of weekend compared with weekday stroke admission on thrombolytic use, in-hospital mortality, discharge disposition, hospital charges, and length of stay in the Nationwide Inpatient Sample Database, 2002 to 2007. Stroke. 2010; 41(10): 2323-8.
  21. Cram P, Hillis SL, Barnett M, et al. Effects of weekend admission and hospital teaching status on in-hospital mortality. Am J Med. 2004; 117(3): 151-7.
  22. Iwan A Meynaar JIvdS, Johannes H Rommes, Margot van SpreuwelVerhejen, et al. Off hour admission to an intensvist-led ICU is not associated with increased mortality. Critical care. 2009; 13(3): R84.
  23. Varnava AM, Sedgwick JEC, Deaner A, et al. Restricted weekend service inappropriately delays discharge after acute myocardial infarction. Heart. 2002; 87(3): 216-9.
  24. Hixson E. Do weekends or evenings matter in a pediatric intensive care unit? Pediatric critical care medicine. 2005; 6(5): 523.
  25. GC Fonarow WA, NM Albert, WG Stough, et al. JB Young Day of addmission and clinical outcomes for patients hospitalized for heart failure/CLINICAL PERSPECTIVE: findings from the organised program to initiate lifesaving treatment in hospitalized patients with heart failure (OPTIMIZE-HF). Circ Heart Fail. 2008; 1: 50-7.
  26. Chalfin D. Impact of delayed transfer of critically ill patients from the emergency department to the intensive care unit. Critical care medicine. 2007; 35(6): 1477.
  27. Rivers E, Nguyen B, Havstad S, et al. Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock. New England Journal of Medicine. 2001; 345(19): 1368-77.
  28. RP Myers CK, AM Shaheen. The effect of weekend versus weekday admission on outcomes of esophageal variceal hemorrhage. Can J Gastroenterol. 2009; 23(7): 495 - 501.
  29. Tissue Plasminogen Activator for Acute Ischemic Stroke. New England Journal of Medicine. 1995; 333(24): 1581-8.
  30. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. The Lancet. 2004; 363(9411): 768-74.
  31. Bernard SA, Gray TW, Buist MD, et al. Treatment of Comatose Survivors of Out-of-Hospital Cardiac Arrest with Induced Hypothermia. New England Journal of Medicine. 2002; 346(8): 557-63.
  32. Mild Therapeutic Hypothermia to Improve the Neurologic Outcome after Cardiac Arrest. New England Journal of Medicine. 2002; 346(8): 549-56.
  33. Anderson JL, Karagounis LA, Califf RM. Metaanalysis of five reported studies on the relation of early coronary patency grades witk mortality and outcomes after acute myocardial infarction. The American Journal of Cardiology. 1996; 78(1): 1-8.
  34. Boersma E, Maas ACP, Deckers JW, Simoons ML. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. The Lancet. 1996; 348(9030): 771-5.
  35. 35. Shaheen AAM, Kaplan GG, Myers RP. Weekend Versus Weekday Admission and Mortality From Gastrointestinal Hemorrhage Caused by Peptic Ulcer Disease. Clinical Gastroenterology and Hepatology. 2009; 7(3): 303-10.
  36. 36. Dorn S, Shah N, Berg B, et al. Effect of Weekend Hospital Admission on Gastrointestinal Hemorrhage Outcomes. Digestive Diseases and Sciences. 2010; 55(6): 1658-66.
  37. Aylin P, Yunus A, Bottle A, et al. Weekend mortality for emergency admissions. A large, multicentre study. Quality and Safety in Health Care. 2010; 19(3): 213-7.
  38. Rooney T, Moloney ED, Bennett K, et al. Impact of an acute medical admission unit on hospital mortality: a 5-year prospective study. QJM. 2008; 101(6): 457-65.
  39. O'Loughlin R, Allwright S, Barry J, Kelly A, Teljeur C. Using HIPE data as a research and planning tool: limitations and opportunities. Ir J Med Sci. 2005; 174(2): 40-5; 52-7.
  40. De Bleser L, Vlayen J, Vanhaecht K, et al. Classifying clinical pathways. Stud Health Technol Inform. 2004; 110: 9-14.
  41. Silke B, Kellett J, Rooney T, et al. An improved medical admissions risk system using multivariable fractional polynomial logistic regression modelling. QJM. 2009; hcp149.
  42. Hosmer D, Lemeshow S. Applied Logistic Regression. New York, USA: John Wiley & Sons; 2000.
  43. Prytherch DR, Sirl JS, Schmidt P, et al. The use of routine laboratory data to predict in-hospital death in medical admissions. Resuscitation. 2005; 66(2): 203-7.
  44. Pine M, Jones B, Lou YB. Laboratory values improve predictions of hospital mortality. Int J Qual Health Care. 1998; 10(6): 491-501.
  45. Smith GB, Prytherch DR. Laboratory risk factors for hospital mortality. QJM. 2008 January 1, 2008; 101(1): 63-.
  46. Woo J, Mak YT, Lau J, Swaminathan R. Prediction of mortality in patients in acute medical wards using basic laboratory and anthropometric data. Postgrad Med J. 1992 Dec; 68(806): 954-60.
  47. Bottle A, Aylin P, Majeed A. Identifying patients at high risk of emergency hospital admissions: a logistic regression analysis. J R Soc Med. 2006; 99(8): 406-14.
  48. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987; 40(5): 373-83.
  49. Barba R, Losa JE, Velasco M, et al. Mortality among adult patients admitted to the hospital on weekends. Eur J Intern Med. 2006; 17(5): 322-4.
  50. Froom P, Shimoni Z. Prediction of hospital mortality rates by admission laboratory tests. Clin Chem. 2006; 52(2): 325-8.

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The increased mortality associated with a weekend emergency admission is due to increased illness severity and altered case-mix

10th March 2016
Authors Affiliations
Olga Mikulich MRCPI, Division of Internal Medicine St James’s Hospital, Dublin 8, Ireland
Elizabeth Callaly MRCPI, Division of Internal Medicine e, St James’s Hospital, Dublin 8, Ireland
Kathleen Bennett PhD Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences
Deirdre O’Riordan MED Directorate, St James’s Hospital, Dublin 8, Ireland.
Bernard Silke MED Directorate, St James’s Hospital, Dublin 8, Ireland.

The increased mortality associated with a weekend emergency admission is due to increased illness severity and altered case-mix

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