How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions

How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions

Objective: To determine factors affecting inpatient sleep and assess the range and effectiveness of non-pharmacological interventions aimed at improving the sleep of patients admitted to regular care wards.
Methods: A systematic literature search was conducted in five scientific databases, including articles published from inception to June 23rd, 2023. Eligible studies evaluated sleep disturbing factors or the effect of non-pharmacological intervention(s). Meta-analyses on intervention studies were conducted using a random effects model. Certainty of evidence was assessed using the GRADE approach.
Results: Out of 591 potentially eligible studies, 229 were included in this review. Sleep disturbers were identified in 153 studies, and 102 studies were eligible for meta-analysis. Common factors contributing to poor sleep included noise, light, care-related interruptions, pain, and anxiety. The meta-analyses revealed large pooled effects in favor of sleep for the use of eye masks and earplugs, headphones and white noise, aromatherapy, massage, muscle relaxation and breathing exercises, and advanced nursing strategies. However, the certainty of the evidence ranged from moderate to very low.
Conclusion: Inpatient sleep is often disturbed by patient-related, care-related, and environmental factors. While there are promising non-pharmacological interventions, the overall quality of studies, heterogeneity in study populations, and differences in outcome measures present challenges for drawing definitive conclusions.

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How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions

26th January 2024
PMID: 38284637
Authors Affiliations
P Burger Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, Netherlands. Amsterdam Reproduction and Development research institute, Amsterdam, The Netherlands
ES Van den Ende Section General Internal Medicine unit Acute Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands
W Lukman Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, Netherlands.
GL Burchell Medical Library, Vrije Universiteit, De Boelelaan 1117, Amsterdam, The Netherlands.
LMH Steur Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, Netherlands.
JAW Polderman Department of Anesthesiology, Amsterdam UMC, Amsterdam, The Netherlands.
H Merten Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
JWR Twisk Department of Clinical Epidemiology and Data Science, Amsterdam Public Health, Amsterdam UMC, the Netherlands
PWB Nanayakkara Section Acute Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, The Netherlands
RJBJ Gemke Department of Pediatrics, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, Netherlands. Amsterdam Reproduction and Development research institute, Amsterdam, The Netherlands

How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions

Cite this article as:

Burger P, Van den Ende ES, Lukman W, Burchell GL, Steur L, Polderman J, Merten H, Twisk J, Nanayakkara P, Gemke R. How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions. Acute Med. 2023;22(4):209-257. PMID: 38284637.

How to improve inpatient sleep in regular care wards: a systematic review and meta-analysis of sleep disturbers and non-pharmacological interventions

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