Valproate-Associated Hyperammonaemic Encephalopathy

Valproate-Associated Hyperammonaemic Encephalopathy

We present the case of a 55 year old who presented multiple times with altered conscious levels. He was often treated as being post-ictal, when in fact, he had Sodium Valproate induced hyperammonaemic encephalopathy. Sodium Valproate can frequently increase ammonia levels, and in some patient lead to hyperammonaemic encephalopathy.

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Valproate-Associated Hyperammonaemic Encephalopathy

28th March 2022
PMID: 35342909
Authors Affiliations
Paul Anthonipillai Medicl Registrar East Surrey Hospital
Gemma Sharp Senior Clinical Pharmacist East Surrey Hospital
Jeffery Kimber Consultant Neurologist East Surrey Hospital
Veqas Ziauddin Consultant in Acute and General Medicine East Surrey Hospital

Valproate-Associated Hyperammonaemic Encephalopathy

Cite this article as:

Anthonipillai P, Sharp G, Kimber J, Ziauddin V. Valproate-Associated Hyperammonaemic Encephalopathy. Acute Med. 2022;21(1):43-46. doi: 10.52964/AMJA.0891. PMID: 35342909.

Valproate-Associated Hyperammonaemic Encephalopathy

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