methaemoglobinaemia

Case Report: Congenital Methaemoglobinaemia Type 1: Benign Cyanosis?

Case Reports, Volume 21, Issue 1, Pages 1-64 (2022)

Type 1 congenital methaemoglobinaemia is a rare cause of cyanosis which may manifest in affected individuals during concomitant illness. Treatment indications and aims differ from that of acquired methaemoglobinaemia. Type 1 methaemoglobinaemia is a distinct condition from the type 2 form which has a high mortality rate in infancy. A 25 year old male with known type 1 congential methaemoglobinaemia presented with cyanosis in the context of Influenza A with raised methaemoglobin levels on arterial blood gas analysis.

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The Experience of a District General Hospital with a Large Outdoor Music Festival in England

Research Audit and Clinical Practice, Volume 16, Issue 2, Pages 49 – 100 (2017)

Objectives: To assess the impact of the Parklife annual music festival on the local hospital, North Manchester General.

Methods: Data was obtained retrospectively by analysis of emergency department records during the weekend of Parklife 2015.

Results: 32 patients were identified, 56% reported taking drugs. 34% were admitted for overnight observation. 4 patients presented with methaemoglobinaemia following oral ingestion of amyl nitrate. One patient had a methaemoglobin fraction of 90.6%, which is amongst the most extreme recorded in literature.

Conclusion: Music festivals can impose a burden on local health services. Organisers should operate an efficient surveillance system in order to prevent the sale and use of recreational drugs, providing adequate on-site health services and working in collaboration with local emergency services.

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