Abstract
Henoch-Schonlein Purpura (HSP) is the most common systemic vasculitis in childhood and can present in adults. It is a self-limiting disease characterised by a tetrad of manifestations including the mandated typical cutaneous hallmark.
We present a classic case of HSP complicated by gastrointestinal haemorrhage associated with hidradenitis suppurativa.
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References
- Ozen S et al. EULAR/PRES endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 2006; 65(7): 936–941.
- Gardner-Medwin JMM. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360: 1197–1202.
- Chang WL et al. Gastrointestinal manifestations in Henoch-Schonlein purpura: a review of 261 patients. Acta Pediatr 2004; 93(11): 1427–1431.
- Calvino MC et al. Henoch-Schonlein purpura in children from northwestern Spain. A 20-year epidemiological and clinical study. Medicine 2001; 80: 279–290.
- Trapani S et al. Henoch-Schonlein purpura in childhood: epidemiological and clinical analysis of 150 cases over a 5-year period and review of literature. Semin Arthr Rheum 2005; 35(3): 143–153.
- Saulsbury FT et al. Henoch-Schonlein purpura in children. Report of 100 patients and review of literature. Medicine 1999; 78(6): 395–409.
- Apostolopoulos P et al. Henoch-Schonlein purpura associated with Campylobacter enterocolitis. J Clin Gastroenterol 1999; 29(4): 346–347.
- Roza M et al. Henoch-Schonlein purpura after Shigellosis. Clin Nephrol 1983; 20(5): 269.
- Youmbissi TJ et al. Henoch-Schonlein nephritis and salmonella typhi septicaemia. Nephrol Dialysis Transplant 2001; 16(5): 1081–1082.
- Sola R. Henoch-Schonlein purpura associated with acetylsalicylic acid. Ann Int Med 1997; 126(8): 665.
- Niedermaier G et al. Henoch-Schonlein syndrome induced by carbidopa/levodopa. Lancet 1997; 349(9058): 1071–1072.
- Zurada JM et al. Henoch-Schonlein purpura associated with malignancy in adults. J Am Acad Dermatol 2006; 55(5 Suppl): S65–S70.
- Esaki M et al. GI involvement in Henoch-Schonlein purpura. Gastrointest Endosc 2002; 56: 920–923.
- Lindenauer SM et al. Surgical aspects of Henoch-Schonlein purpura. Surgery 1966; 59(6): 982–987.
- Pillebout E et al. Henoch-Schonlein purpura in adults: outcome and prognostic factors. J Am Soc Nephrol 2002; 13(5): 1271–1278.
- Narchi H. Risk of long-term renal impairment and duration of follow-up recommended for Henoch-Schonlein purpura with normal or minimal urinary findings: a systematic review. Arch Dis Childhood 2005; 90(9): 916–920.
- Kato S et al. Intestinal IgA deposition in Henoch-Schonlein purpura with severe gastro-intestinal manifestations. Eur J Pediatr 1996; 155(2): 91–95.
- Connolly B, Halpin D. Sonographic evaluation of the abdomen in Henoch-Schonlein purpura. Clin Radiol 1994; 49(5): 320–323.
- Ozdemir H et al. Sonographic demonstration of intestinal involvement in Henoch-Schonlein syndrome. Eur J Radiol 1995; 20(1): 32–34.
- Cappell MS et al. Colonic lesions associated with Henoch-Schonlein purpura. Am J Gastroenterol 1990; 85(9): 1186–1188.
- Kawasaki M et al. Ileitis caused by Henoch-Schonlein purpura. An endoscopic view of the terminal ileum. J Clin Gastroenterol 1997; 25(1): 396–398.
- Karagozian R et al. Henoch-Schonlein purpura presenting with ileal involvement in an adult. Dig Dis Sci 2004; 49(10): 1722–1726.
- Saulsbury FT et al. Crohn’s disease presenting with Henoch-Schonlein purpura. J Paediatr Gastroenterol Nutr 2000; 31(2): 173–175.
- Church JM et al. The differential diagnosis and comorbidity of hidradenitis suppurativa and perianal Crohn’s disease. Int J Colorectal Dis 1993; 8(3): 117–119.
- Ronkainen J et al. Early prednisolone therapy in Henoch-Schonlein purpura: a randomised, double-blind, placebo-controlled trial. J Paediatr 2006; 149(2): 241–247.
- Huber Am et al. A randomised, placebo-controlled trial of prednisolone in early Henoch-Schonlein purpura. BMC Medicine 2004; 2: 7.
- Weiss PF et al. Effects of corticosteroid on Henoch-Schonlein purpura: a systematic review. Paediatrics 2007; 120: 1079–1087.
- Blanco R et al. Henoch-Schonlein purpura in adulthood and childhood: two different expressions of the same syndrome. Arthr Rheum 1997; 40(5): 859–864.
- Uppal SS et al. Henoch-Schonlein’s purpura in adults versus children/adolescents: A comparative study. Clin Exp Rheum 2006; 24(2 Suppl 41): S26–S30.
- Garcia-Porrua C et al. Henoch-Schonlein purpura in children and adults: clinical differences in a defined population. Semin Arthr Rheum 2002; 32(3): 149–156. R
