Abstract

The severe sequelae of infection from the conventionally termed ‘benign’ forms of malaria are being increasingly recognised, and delayed diagnosis and treatment lead to worse outcomes. The clinical picture can be non-specific and malaria epidemiology is constantly changing, presenting challenges for the acute clinician. The most critical step in the diagnosis of patients presenting in the UK is the clinician’s awareness of the disease and its key presenting features. We describe a case of Plasmodium vivax malaria in a young man who presented with fever and diarrhoea, who had never travelled to a recognised malaria-endemic area.

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References

1. The Health Protection Agency Malaria Reference Laboratory. Available from: http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Malaria/EpidemiologicalData/ malaEpi10CasesandDeaths/ [Internet].
2. Checkley AM, Smith A, Smith V, et al. Risk factors for mortality from imported falciparum malaria in the united kingdom over 20 years: An observational study. BMJ 2012; 344.
3. Guerra CA, Snow RW, Hay SI. Mapping the global extent of malaria in 2005. Trends Parasitol 2006; 22(8): 353-8.
4. Price RN, Tjitra E, Guerra CA, et al. Vivax malaria: Neglected and not benign. Am J Trop Med Hyg 2007; 77(6 Suppl): 79-87.
5. Price RN, Douglas NM, Anstey NM. New developments in plasmodium vivax malaria: Severe disease and the rise of chloroquine resistance. Curr Opin Infect Dis 2009; 22(5): 430-5.
6. Tanios MA, Kogelman L, McGovern B, et al. Acute respiratory distress syndrome complicating plasmodium vivax malaria. Crit Care Med 2001; 29(3): 665-7.
7. Zaki SA, Shanbag P. Acute glomerulonephritis: An unusual manifestation of plasmodium vivax malaria. Ann Trop Paediatr 2011; 31(2): 181-4.
8. Beg MA, Khan R, Baig SM, et al. Cerebral involvement in benign tertian malaria. Am J Trop Med Hyg 2002; 67(3): 230-2.
9. Mendis K, Sina BJ, Marchesini P, et al. The neglected burden of plasmodium vivax malaria. Am J Trop Med Hyg 2001; 64(1-2 Suppl): 97-106.
10. Taylor SM, Molyneux ME, Simel DL, et al. Does this patient have malaria? JAMA 2010; 304(18): 2048-56.
11. Shin EH, Guk SM, Kim HJ, et al. Trends in parasitic diseases in the republic of korea. Trends Parasitol 2008; 24(3): 143-50.
12. Center for disease control [Internet]. Available from: http:// wwwnc.cdc.gov/travel/destinations/south-korea.htm.
13. Oh MD, Shin H, Shin D, et al. Clinical features of vivax malaria. Am J Trop Med Hyg 2001; 65(2): 143-6.
14. [Internet].National Travel Health Network and Centre. Available from: http://www.nathnac.org/ds/c_pages/country_page_kr.htm.
15. Feachem RG, Phillips AA, Hwang J, et al. Shrinking the malaria map: Progress and prospects. Lancet 2010; 376(9752): 1566-78.