Eosinophilic fasciitis: experience with a patient and review of the potential mimics

Eosinophilic fasciitis: experience with a patient and review of the potential mimics

Bilateral lower limb swelling is a common clinical scenario with a wide differential diagnosis. We present a young man with gradually worsening bilateral leg swelling, who was diagnosed with eosinophilic fasciitis.
A 20 year old Hispanic male presented with a six week history of bilateral lower limb pain and swelling, later involving the upper limbs, but sparing the hands, feet and face. He had initial pitting, followed by non-pitting oedema and had a positive ‘groove sign’. With peripheral eosinophilia, a clinical diagnosis of eosinophilic fasciitis was suspected and was later confirmed on histology. He improved with prednisolone initially and is currently maintained on tapering prednisolone alongside methotrexate.

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Eosinophilic fasciitis: experience with a patient and review of the potential mimics

22nd January 2022
PMID: 35072386
Authors Affiliations
Chathurika Lakmini Dandeniya MBBS (Peradeniya, Sri Lanka), MD (Colombo, Sri Lanka), MRCP (London) Clinical Fellow Higher, Department of Rheumatology, Addenbrooke’s Hospital, Cambridge University Hospitals Trust, UK Lecturer, Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka
Maeve Fifield MBBS, MA Hons (Cantab), MRCP Specialty trainee in Rheumatology, Department of Rheumatology, Addenbrooke’s Hospital, Cambridge University Hospitals Trust, UK
Caroline Lebus MBBS, FRCP (London), DRCOG, PG Cert Med Ed Consultant in Acute Internal Medicine, Addenbrooke’s Hospital, Cambridge University Hospitals Trust, UK
Nicholas Shenker MB BCh (Cantab), MA (Cambridge), BM (Oxon), PhD, FRCP (London) Consultant in Rheumatology, Department of Rheumatology, Addenbrooke’s Hospital, Cambridge University Hospitals Trust, UK

Eosinophilic fasciitis: experience with a patient and review of the potential mimics

Cite this article as:

Dandeniya C, Fifield M, Lebus C, Shenker N. Eosinophilic fasciitis: experience with a patient and review of the potential mimics. Acute Med. 2021;20(4):282-285. doi: 10.52964/AMJA.0879. PMID: 35072386.

Eosinophilic fasciitis: experience with a patient and review of the potential mimics

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