Abstract
Sarcoidosis is a cryptogenic multisystem granulomatous disorder. We present three patients who presented acutely with erythema nodosum in our Medical Assessment Unit (MAU) or attended our clinic, subsequently diagnosed with acute sarcoidosis. In doing so, we aim to demonstrate that this presentation can easily be seen on the acute medical take, focussing on the management of acute sarcoidosis in association with erythema nodosum. Although patients will often not display florid systemic upset on presentation, we recommend follow-up after initial presentation, to ensure good resolution of symptoms.
[download-attachments container="div" style="list" dipslay_icon="1" display_count="1" display__size="0"]
References
- The Diffuse Parenchymal Lung Disease Group of the British Thoracic Society (1999) Patient Information for Sarcoidosis In: The Diagnosis, Assessment and Treatment of Diffuse Parenchymal Lung Diseases in Adults. Thorax 54: Appendix 8.
- Newman, LS, Rose, CS, Bresnitz, EA, et al. A Case Control Etiologic Study of Sarcoidosis: Environmental and Occupational Risk Factors. Am J Respir Crit Care Med
2004; 170: 1324. - Mehra, NK, Bovornkitti, S. HLA and sarcoidosis. Sarcoidosis 1988; 5: 87.
- Macaron NC, Cohen C, Chen SC, Arbiser JL. gli-1 Oncogene is highly expressed in granulomatous skin disorders, including sarcoidosis, granuloma annulare, and
necrobiosis lipoidica diabeticorum. Arch Dermatol. Feb 2005; 141(2): 259–62. - Marzouk K, Saleh S, Kannass M, Sharma OP. Interferon-induced granulomatous lung disease. Curr Opin Pulm Med. Sep 2004; 10(5): 435–40.
- Hunninghake GW, Crystal RG. Mechanisms of Hypergammaglobulinemia in Pulmonary Sarcoidosis. J Clin Invest 1981. 67(1): 86–92.
- Iannuzzi MC, Rybicki BA, Teirstein AS. Sarcoidosis NEJM 2007; 357: 2153–65.
- Wolff K, Johnson RA, Suurmound D. Sarcoidosis In: Fitzpatrick’s Color Atlas & Synopsis of Clinical Dermatology 2005; 5th ed. New York, McGraw Hill.
- Laohaburanakit P, Chan A. Obstructive sarcoidosis. Clin Rev Allergy Immunol. 2003; 52: 115–29.
