Acute Management of Guillain-Barré Syndrome

Acute Management of Guillain-Barré Syndrome

Abstract

Guillain-Barré Syndrome (GBS) is an acute inflammatory polyneuropathy. Typical presentation is one of ascending tetraparesis with aref lexia. Variant forms of GBS include ataxia and ophthalmoplegia with aref lexia; patients with preserved ref lexes may mislead the unwary. Diagnostic dilemmas may be solved with neurophysiology and lumbar puncture.

Emergency management requires assessment of airway, breathing and circulation. Regular monitoring of respiratory, and bulbar function is essential and any deterioration in neurological function should prompt treatment. Treatment with intravenous immunoglubulin shortens the length of illness.
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References

  1. Raphael J-C, Chevret S, Hughes RAC, Annane D. Plasma exchange for Guillain-Barré syndrome (Cochrane Review). 2001 Cochrane Library 2. Oxford.
  2. Hughes RAC, Raphael J-C, Swan AV and van Doorn PA. Intravenous immunoglobulin for Guillain-Barré syndrome (Cochrane Review). 2001 Cochrane Library 3. Oxford.
  3. Protocol for using Intravenous immunoglobulins. Available on the Association of British Neurology website at :www.theabn.org.uk
  4. GBS Society telephone number: 0800 374803 and the website address is www.gbs.org.uk

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Acute Management of Guillain-Barré Syndrome

11th February 2016
Authors Affiliations
Charlotte Lawthom BA MRCP Department of Neurology Royal Gwent Hospital Cardiff Road Newport NP20 2MB
J Gareth Llewelyn BSc MD FRCP Department of Neurology Royal Gwent Hospital Cardiff Road Newport NP20 2MB

Acute Management of Guillain-Barré Syndrome

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Acute Management of Guillain-Barré Syndrome

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