Anaphylaxis

Improving medical workforce knowledge of adrenaline (epinephrine) administration in treatment of anaphylaxis in adults

Original Articles, Volume 20, Issue 2, Pages 89-156 (2021)

Aim: To compare results of repeated surveys (2010, 2015 and 2017) regarding the knowledge of the medical workforce potentially involved in adrenaline administration for the emergency treatment of anaphylaxis in adults.

Methods: Convenience samples of medical (and advanced nursing) staff were surveyed on three separate occasions (2010, 2015 and 2017). Several educational methods were used to increase awareness of the specific administration of adrenaline.

Results: Overall, knowledge of the medical workforce regarding correct first dose adrenaline administration improved from 15% in 2010 to 49% in 2015 and finally 63% in 2017.

Conclusion: This survey comparison shows knowledge of the medical workforce regarding adrenaline administration for treatment of anaphylaxis in adults can be significantly improved by employing a variety of educational methods.

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Scombrotoxin poisoning: an important differential diagnosis for anaphylaxis

Case Reports, Volume 9, Issue 2, Pages 53 - 96 (2010)

Abstract

We report a case of scombrotoxin poisoning, an acute illness that develops within minutes to hours of eating poorly processed oily fish, such as tuna or mackerel. It presents with symptoms that can mimic an anaphylactic reaction. It is presumed to arise due to ingestion of histamine that is formed by contaminating bacteria that have flourished during periods of suboptimal refrigeration, following capture. Knowledge of this underdiagnosed malady as a potential differential diagnosis for patients presenting with symptoms suggestive of histamine release is important. It is a notifiable condition. The alternative diagnosis of anaphylaxis may have significant lifestyle implications for the patient. This article reports on one such presentation and the way that the diagnosis was explored.

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Anaphylaxis – A guide to diagnosis, management and follow up

Original Articles, Volume 1, Issue 2, Pages 33 - 76 (2002)

Abstract

Anaphylaxis is a severe, potentially life threatening allergic reaction which occurs in adults and children. Prompt diagnosis and appropriate acute medical management will prevent fatal anaphylactic episodes. Anaphylactic reactions are IgE mediated responses to foreign antigens to which there has been previous exposure. The foreign antigens commonly implicated in anaphylaxis are foods (particularly nuts), drugs and venoms. Long term management should involve liaison with an immunologist/allergist to identify an underlying cause, provide education for further prevention and where possible offer immunotherapy.

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