Background: Long-term outcomes after acute medical and surgical illness are largely unknown.

Aim: To describe cognitive and physical function, health-related quality of life and risk of anxiety and depression after acute illness.

Design: Prospective cohort study.

Methods: Home visit at three and twelve months measuring: Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Chelsea Critical Care Physical Assessment tool, Short Form Health Survey, Hospital Anxiety and Depression Scale and Trail Making Test.

Results: Of 101 included patients, 60 were visited at three and 36 at twelve months. The RBANS value was 84 (69-96) at three months and 88 (69-101) at twelve months.

Conclusions: We found a moderately reduced cognitive function three and twelve months after acute illness.

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Refernces

1. Myers EA, Smith DA, Allen SR, et al. Post-ICU syndrome. J Am Acad Physician Assist. 2016;29:34–37.
2. Huang C, Mårtensson J, Gögenur I, et al. Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review. Neural Plast. 2018;1:1–12.
3. Girard TD, Self WH, Edwards KM, et al. Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia: a Prospective Cohort Study. J Gen Intern Med. 2018;33:929–935.
4. Von Elm E, Altman DG, Egger M, et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies. Ann Intern Med. 2007;147:573–577.
5. Burcharth J, Abdulhady L, Danker J, et al. Implementation of a multidisciplinary perioperative protocol in major emergency abdominal surgery. Eur J Trauma Emerg Surg. Epub ahead of print DOI: 10.1007/s00068-019-01238-7.
6. Tengberg LT, Bay-Nielsen M, Bisgaard T, et al. Multidisciplinary perioperative protocol in patients undergoing acute high-risk abdominal surgery. Br J Surg. 2017;104:463–471.
7. Randolph C, Tierney MC, Mohr E, et al. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): Preliminary Clinical Validity. J Clin Exp Neuropsychol.1998;20:310–319.
8. Corner EJ, Wood H, Englebretsen C, et al. The Chelsea Critical Care Physical Assessment Tool (CPAx): Validation of an innovative new tool to measure physical morbidity in the general adult critical care population; An observational proof-of-concept pilot study. Physiother (United Kingdom). 2013;99:33–41.
9. Brazier JE, Harper R, Jones NM, et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160–164.
10. Zigmond AS, Snaith RP. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand. 1983;67:361–370.
11. Reitan RM. The relation of the Trail Making Test to organic brain damage. J Consult Psychol. 1955;19:393–394.
12. de la Vega R, Tomé-Pires C, Solé E, et al. The Pittsburgh sleep quality index: Validity and factor structure in young people. Psychol Assess. 2015;27:e22–e27.
13. Morin CM, Belleville G, Bélanger L, et al. The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep. 2011;34:601–8.
14. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14:540–5. Estrup S, Kjer CKW, Vilhelmsen F, et al. Cognitive Function 3 and 12 Months After ICU Discharge—A Prospective Cohort Study. Crit Care Med. 2018;46:e1121–e1127.
15. Duff K, Humphreys Clark JD, O’Bryant SE, et al. Utility of the RBANS in detecting cognitive impairment associated with Alzheimer’s disease: Sensitivity, specificity, and positive and negative predictive powers. Arch Clin Neuropsychol. 2008;23:603– 612.
16. McKay C, Casey JE, Wertheimer J, et al. Reliability and validity of the RBANS in a traumatic brain injured sample. Arch Clin Neuropsychol. 2007;22:91–98.
17. Lee L, Heckman G, Molnar FJ. Frailty: Identifying elderly patients at high risk of poor outcomes. Can Fam Physician. 2015;61:227–31.
18. Adam U, Habazettl H, Graefe K, et al. Health-related quality of life of patients after surgery for acute Type A aortic dissection. Interact Cardiovasc Thorac Surg. 2018;27:48–53.
19. Jussli-Melchers J, Panholzer B, Friedrich C, et al. Long-term outcome and quality of life following emergency surgery for acute aortic dissection type A: A comparison between young and elderly adults. Eur J Cardio-thoracic Surg. 2017;51:465–471.
20. Herridge MS, Cheung AM, Tansey CM, et al. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med. 2003;348:683–693.
21. Kumar M, Nayak PK. Psychological sequelae of myocardial infarction. Biomed Pharmacother. 2017;95:487–496.
22. Giovagnoli AR, Del Pesce M, Mascheroni S, et al. Trail Making Test: Normative values from287 normal adult controls. Ital J Neurol Sci. 1996;17:305–309.
23. Wilk CM, Gold JM, Bartko JJ, et al. Test-retest stability of the Repeatable Battery for the Assessment of Neuropsychological Status in schizophrenia. Am J Psychiatry. 2002;159:838–844.
24. Duff K, Beglinger LJ, Schoenberg MR, et al. Test-retest stability and practice effects of the RBANS in a community dwelling elderly sample. J Clin Exp Neuropsychol. 2005;27:565–575.