Home»Research Audit and Clinical Practice»Problem-based review: Immune-mediated complications of ‘Checkpoint Inhibitors’ for the Acute Physician

Problem-based review: Immune-mediated complications of ‘Checkpoint Inhibitors’ for the Acute Physician


Immunotherapy with ’checkpoint-inhibitors‘ has significantly improved outcomes for patients with a range of malignancies. However, significant immune-mediated toxicities of these therapies are well-described. These immune-mediated toxicities can affect virtually all organ systems and are potentially fatal. The timing of onset of the adverse effects is dependent on the organ system affected and…

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