Home»Clinical Reviews»Controversies in acute medicine: Oxygen therapy for exacerbations of chronic obstructive pulmonary disease (COPD)

Controversies in acute medicine: Oxygen therapy for exacerbations of chronic obstructive pulmonary disease (COPD)


Abstract Some patients with COPD ‘retain CO2’ when given high concentration or uncontrolled oxygen therapy. The mechanism for this, and why it occurs in only some patients, is unclear. The pathogenesis of chronic hypercapnia in COPD involves multiple, poorly understood mechanisms. During acute exacerbations ‘CO2 retention’ is thought to occur…

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